Follow the directions on the prescription label. The dose is taken 1 hour before sexual activity.

5.9 Renal Impairment

Yes; grapefruit compounds inhibit CYP3A4 and can unpredictably raise drug levels, increasing side-effect risk. Even one glass may alter metabolism; consistent, limited intake or complete avoidance is advisable to maintain predictable exposure. Are over-the-counter sexual enhancers safe with vardenafil? Many contain undeclared PDE5 analogues or nitrates, posing serious interaction risks; avoid concurrent use. What if I experience dizziness after dosing?

Available Strengths (2)·Most prescribed

Sit or lie down until symptoms pass; if severe or persistent, seek medical attention as this may indicate significant hypotension. No evidence supports physical dependence, but psychological reliance on performance medications can develop, warranting periodic assessment. How effective is vardenafil compared with other PDE5 inhibitors? Trials report 70-80 % successful intercourse attempts versus 50-60 % with placebo, comparable to sildenafil and tadalafil. Macrolides such as clarithromycin inhibit CYP3A4 and can raise vardenafil levels, necessitating dose adjustment. Do not take your medication more often than directed. Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Sudden vision loss in one or both eyes Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).

Product	Dosage	Quantity + Bonus	Price
Kamagra	100mg	32 Pills	121.24€ 115.47€
Kamagra 100 mg	100 mg	12 Pills	55.64€ 52.99€
Viagra Generic	200mg	60 + 4 Pills	125.19€ 119.23€
Cialis Generic	10mg	30 + 4 Pills	63.32€ 60.30€
Cialis Generic	40mg	60 + 6 Pills	130.98€ 124.74€
Cialis Generic	10mg	120 + 6 Pills	178.49€ 169.99€
Kamagra Oral Jelly	100 mg	110 + 9 Sachets	334.87€ 318.92€
Cialis Generic	20mg	10 Pills	31.49€ 29.99€
Cialis Generic	5mg	60 + 4 Pills	86.02€ 81.92€
Viagra Generic	150mg	180 + 10 Pills	236.46€ 225.20€
Viagra Soft Tabs	100mg	10 Pills	36.93€ 35.17€

Keep in the original blister package until time of use. Throw away any unused medication after the expiration date.

5.6 Alpha-Blockers

The American Journal of Cardiology, 93(9), 1378-1383. Pharmacology and drug-interaction effects of phosphodiesterase 5 inhibitors. International Journal of Clinical Practice, 59(9), 1165-1170. Ocular side effects of vardenafil: Results of a double-blind study. The Journal of Sexual Medicine, 17(11), 2057-2065.

What are the serious side effects of vardenafil?

Cardiac safety in clinical trials of PDE5 inhibitors. Cardiology in Review, 13(4), 213-220. Simultaneous administration of vardenafil and tamsulosin in benign prostatic hyperplasia. Optimization of factors affecting vardenafil absorption using β-cyclodextrin. Pharmaceutical Development and Technology, 24(3), 354-364. We found up to 60% of Levitra products sold online were falsified. The falsified products contained sildenafil or tadalafil instead of vardenafil. Handheld NIR and Raman could discriminate between genuine and falsified products. It is often reported that falsified medicines have harmful effects on patients both Japan and abroad.

Are there any dosage adjustments for certain people?

Because mechanistic data suggest theoretical impacts on vascular tone, the risk-benefit ratio for any off-label maternal use (e.g., pulmonary hypertension) remains uncertain. Current FDA guidance on reproduction-development toxicity testing stipulates that embryo-fetal development studies in at least two species (usually rats and rabbits) inform labeling when systemic maternal exposure approximates or exceeds anticipated clinical exposure. Safety extrapolation to humans relies on allometric scaling, placental transfer kinetics, and species-specific pharmacodynamics; therefore, absent positive human data, vardenafil should be avoided throughout pregnancy, and effective contraception is advised for women of reproductive potential participating in investigational protocols. Store vardenafil tablets at controlled room temperature, 20-25 °C (68-77 °F), with permissible excursions between 15 °C and 30 °C. Vardenafil for the treatment of erectile dysfunction: A critical review.

Important Disclaimer

Phosphodiesterase 5: Structure-function regulation and selectivity. PubChem compound summary for CID 135400189, vardenafil. Risk of death in patients with coronary artery disease taking phosphodiesterase 5 inhibitors. Journal of the American College of Cardiology, 82(12), 1123-1135. Evaluation of vardenafil on cardiac repolarization in healthy men. In this study, we purchased vardenafil tablets on the internet and investigated their quality and authenticity using visual observations, authenticity investigations, non-destructive tests (handheld NIR and Raman spectroscopy), and quality analyses (active ingredient content and tablet dissolution rate).

What other information should I know?

Daily use is not approved; the safety database supports on-demand dosing only, with insufficient data on chronic daily administration. 503A pharmacies compound products for specific patients whose prescriptions are sent by their healthcare provider. 503B outsourcing facilities compound products on a larger scale (bulk amounts) for healthcare providers to have on hand and administer to patients in their offices. Our team of experts has the answers you're looking for. A clinical tadalis oral jelly pharmacist cannot recommend a specific doctor. We used genuine 20-mg Levitra tablets that were sold in Japan and tablets from Bayer AG (Germany) as controls. In April 2015, we obtained 28 samples from 15 websites on the internet.

The safety profile of vardenafil is well established.
It is not recommended for use with other ED drugs.
Physical activity while on vardenafil may enhance effectiveness.
Notify your doctor if you experience severe pain.

Our authenticity investigations revealed that 11 (40%) were genuine products and 17 (60%) were falsified products.

5.8 Hepatic Impairment

Korean Journal of Urology, 47(9), 1001-1008. Interactions between grapefruit juice and cardiovascular drugs. American Journal of Cardiovascular Drugs, 4(5), 281-297. American Journal of Cardiology, 92(8), 1048-1053. Clinical pharmacology review of vardenafil NDA 21-400.

What are some side effects that I need to call my doctor about right away?

Simultaneous administration of vardenafil and tamsulosin does not cause hypotension. Grapefruit juice-drug interactions: A practical review. Co-administration is possible, but only after the α-blocker dose is stabilized; otherwise, symptomatic hypotension may occur. If I am already on tamsulosin, how long should I wait before taking vardenafil? Clinical studies suggest dosing vardenafil at least two hours after tamsulosin minimizes additive blood-pressure effects. Handheld NIR and Raman results revealed that the falsified products had different spectra to the genuine products. Principal component analysis of the NIR and Raman spectra showed variation among the falsified products.

Side Effect	Frequency	Severity	Recommended Action
Headache	Common	Mild	Take analgesics, hydration
Flushing	Common	Mild	Cool environment, hydrate
Nasal Congestion	Moderate	Mild	Use decongestants if needed
Dizziness	Less common	Mild	Sit or lie down immediately
Muscle Pain	Rare	Mild	Consult doctor if persists

The 11 genuine products were of good quality, and the 17 falsified products were of poor quality. The falsified products contained sildenafil (the active ingredient of Viagra) or tadalafil (the active ingredient of Cialis) instead of vardenafil. Our results show that falsified Vardenafil tablets are sold on the internet and that it is important to prevent illegal internet sales and increase consumer awareness of the presence of falsified medicines.

What happens if the prescriber decides treatment is not suitable?

They need to know if you have any of these conditions: Anatomical deformation of the penis, Peyronie's disease, or history of priapism (painful and prolonged erection) Eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa Heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems History of blood diseases, like sickle cell anemia or leukemia An unusual or allergic reaction to vardenafil, sorbitol, fructose, other medications, foods, dyes, or preservatives Place the tablet on the tongue and allow it to dissolve, then swallow. Do not crew, crush, or split the tablet. Take the tablet as soon as it is removed from its blister packaging. This medication should be taken without liquid. You may take this medication with or without meals. Applies to the following strengths: 2.5 mg; 5 mg; 10 mg; 20 mg Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity. Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability. Maximum dose: 20 mg once a day Initial dose: 5 mg orally once a day Sexual stimulation is required for a response to treatment. A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers. Patients taking alpha-blockers should not initiate vardenafil therapy with the orally disintegrating tablet. Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity Comments: Sexual stimulation is required for a response to treatment. CrCl: 30 to 80 mL/min: No adjustment recommended. Comment: The orally disintegrating tablet (brand Staxyn) can be used in patients with mild, moderate or severe renal impairment.

Warnings & Precautions

Because we are licensed in all 50 states*, we can accept prescriptions from many licensed prescribers if the prescription is written within their scope of practice and with a valid patient-practitioner relationship. Each injectable IV product will have the osmolarity listed on the label located on the vial. Given the vastness and uniqueness of individualized compounded formulations, it is impossible to list every potential compound we offer. To inquire if we currently carry or can compound your prescription, please fill out the form located on our Contact page or call us at (877) 562-8577. We source all our medications and active pharmaceutical ingredients from FDA-registered suppliers and manufacturers. Mild hepatic dysfunction (Child-Pugh A): No adjustment recommended.

Vardenafil is available by prescription only.
Common side effects include headache and flushing.
It should be taken on an empty stomach for best results.
Do not combine vardenafil with nitrates.

Moderate hepatic dysfunction (Child-Pugh B): 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity. The maximum dose should not exceed 10 mg. Severe hepatic dysfunction (Child-Pugh C): Use should be avoided. Comment: The orally disintegrating tablets should not be used in patients with moderate (Child-Pugh B) or severe (Child-Pugh C) hepatic dysfunction. The dose may be increased to a maximum recommended dose of 20 mg or decreased to 5 mg based on efficacy and side effects.

Vardenafil efficacy depends on proper dosage and timing.
It is generally safe when used as directed.
Patients should avoid heavy meals before intake.
Follow-up with your healthcare provider regularly.