How should I take sildenafil?

By blocking a specific chemical — phosphodiesterase-5 — that normally signals to the body that it’s time for an erection to stop, the drugs effectively encourage blood flow to the genital region in order to allow normal, healthy erections of sufficient duration.31 For most men with ED, these prescription medications eliminate the hardships and frustrations of ED. The other active ingredients in products like Gold— namely, apomorphine and oxytocin — can offer complementary benefits to PDE5 inhibitors that could make them superior choices for men with treatment-resistant ED or dysfunction that arises through multiple channels (e.g., neurochemical, psychological, etc.). Let’s look more closely at BlueChew Gold’s medications to see how they can help men with ED achieve reliable erections. Because Gold contains tadalafil, it should last for up to 36 hours. But the effects of the sildenafil in Gold should wear off before then, meaning each dose would peak in strength around 15-60 minutes after consumption and remain at its peak for about 6-8 hours.3 2 30 Gold is BlueChew’s most ambitious product, a combination of two well-known and effective PDE5 inhibitors in sildenafil and tadalafil alongside two less common ED treatments, apomorphine and oxytocin.

More common

Apomorphine is a dopamine agonist that can potentially improve the neurochemical signaling involved in achieving and maintaining an erection, while oxytocin has been shown to improve symptoms of depression and anxiety, potentially thwarting mental health issues that can contribute significantly to ED.36 24 BlueChew offers three dose 150mg sildenafil for sale options for Gold, so you and your consulting physician can dial in the dose that works best for you. Here’s how each level is dosed: At the base strength, you get a solid middle-ground dose for sildenafil alongside a slightly higher-than-normal dose for as-needed tadalafil, which typically starts at around 5mg and tops out around 20mg in most research.32 33 That introductory dose also gives you 2mg of apomorphine, which is the lowest oral dose shown effective at treating ED.54 The 160IU oxytocin dose is harder to validate. Research into oxytocin’s use in depression and anxiety shows success at a dose of 24IU, but it’s important to remember that this was administered intranasally.26 BlueChew Gold’s 160IU, 200IU, and 240IU doses don’t have direct research related to sublingual administration. That said, sublingual administration should still provide better bioavailability than regular digestion, so these doses could and should be effective. The High and Extra Strength doses reach even further with each medication. The company then added vardenafil, a sildenafil alternative and the generic equivalent of Levitra. After that, the company launched its daily tadalafil and MAX and VMAX combination medications. Most recently, BlueChew’s catalog has coalesced around its most promising product, especially for men with treatment-resistant ED: BlueChew Gold. Gold combines four ED medications to tackle the problem from multiple angles. Sildenafil: A PDE5 inhibitor and the active ingredient in Viagra, sildenafil works in as little as 15 minutes and lasts up to eight hours.2 Tadalafil: Another PDE5 inhibitor and the active ingredient in Cialis. Tadalafil kicks in after as little as 15 minutes and lasts up to 36 hours.3 Apomorphine: A dopamine agonist that supports erectile performance by improving brain chemistry.36 Oxytocin: The so-called “love hormone,” oxytocin can improve mental health markers like depression and anxiety, which can worsen or even cause ED.24 For most men with ED, the combined ingredients in BlueChew Gold will be effective in treating erectile dysfunction.27 28 This means most men will be able to use it in order to achieve an erection of sufficient strength and duration for sex. BlueChew’s innovation on these traditional and effective medications is that it offers them combined as multitherapies able to dissolve under the tongue to start working even faster.29 Sildenafil (the active ingredient in Viagra) has been proven effective in numerous clinical studies, as has tadalafil (the active ingredient in Cialis).2 3 Sildenafil and tadalafil are classified as PDE5 inhibitors. By blocking a specific chemical — phosphodiesterase-5 — that normally signals to the body that it’s time for an erection to stop, the drugs effectively encourage blood flow to the genital region in order to allow normal, healthy erections of sufficient duration.31 For most men with ED, these prescription medications eliminate the hardships and frustrations of ED. The other active ingredients in products like Gold— namely, apomorphine and oxytocin — can offer complementary benefits to PDE5 inhibitors that could make them superior choices for men with treatment-resistant ED or dysfunction that arises through multiple channels (e.g., neurochemical, psychological, etc.). Let’s look more closely at BlueChew Gold’s medications to see how they can help men with ED achieve reliable erections. Because Gold contains tadalafil, it should last for up to 36 hours.

Product	Dosage	Quantity + Bonus	Price
Viagra Generic	50mg	10 Pills	26.87€ 25.59€
Kamagra	100mg	32 Pills	121.24€ 115.47€
Viagra Generic	200mg	90 + 6 Pills	170.79€ 162.66€
Viagra Generic	150mg	90 + 6 Pills	147.18€ 140.17€
Viagra Generic	100mg	30 + 4 Pills	60.91€ 58.01€
Kamagra Soft Tabs	100mg	84 + 4 Pills	233.05€ 221.95€
Viagra Generic	25mg	270 + 8 Pills	184.26€ 175.49€
Kamagra	100mg	20 Pills	86.09€ 81.99€
Viagra Generic	50mg	60 + 4 Pills	83.93€ 79.93€
Viagra Generic	25mg	90 + 6 Pills	105.03€ 100.03€
Viagra Generic	150mg	60 + 4 Pills	111.25€ 105.95€
Kamagra Polo	100mg	272 + 12 Pills	622.94€ 593.28€
Kamagra	100mg	180 + 6 Pills	436.79€ 415.99€

But the effects of the sildenafil in Gold should wear off before then, meaning each dose would peak in strength around 15-60 minutes after consumption and remain at its peak for about 6-8 hours.3 2 30 Gold is BlueChew’s most ambitious product, a combination of two well-known and effective PDE5 inhibitors in sildenafil and tadalafil alongside two less common ED treatments, apomorphine and oxytocin. Apomorphine is a dopamine agonist that can potentially improve the neurochemical signaling involved in achieving and maintaining an erection, while oxytocin has been shown to improve symptoms of depression and anxiety, potentially thwarting mental health issues that can contribute significantly to ED.36 24 BlueChew offers three dose 150mg sildenafil for sale options for Gold, so you and your consulting physician can dial in the dose that works best for you.

Parameter	Value	Unit	Notes
Tmax (Time to peak)	30-60	minutes	When the maximum plasma concentration occurs
Half-life	4-5	hours	Duration of drug activity
Bioavailability	40-50	%	Fraction of drug absorbed into circulation
Onset of Action	15-30	minutes	Time until effect begins

Here’s how each level is dosed: At the base strength, you get a solid middle-ground dose for sildenafil alongside a slightly higher-than-normal dose for as-needed tadalafil, which typically starts at around 5mg and tops out around 20mg in most research.32 33 That introductory dose also gives you 2mg of apomorphine, which is the lowest oral dose shown effective at treating ED.54 The 160IU oxytocin dose is harder to validate. Research into oxytocin’s use in depression and anxiety shows success at a dose of 24IU, but it’s important to remember that this was administered intranasally.26 BlueChew Gold’s 160IU, 200IU, and 240IU doses don’t have direct research related to sublingual administration. That said, sublingual administration should still provide better bioavailability than regular digestion, so these doses could and should be effective. The High and Extra Strength doses reach even further with each medication. Let’s take a close look now at each ingredient in Gold, to better understand how they fight ED: Whether or not most men realize it, this is the most well-known medication for fighting ED; it’s the generic form of Viagra, the original little blue pill. Once it kicks in, which takes about 30-60 minutes, it lasts between four and six hours.

Related/similar drugs

For the many men affected by ED, the condition can be an unfortunate source of embarrassment and frustration. It’s important to remember that this is a very common health condition, and treatment options are available. BlueChew is worth exploring if you’ve noticed difficulty getting or keeping an erection in order to enjoy sex. Through the medical consultation, BlueChew will be able to determine if your underlying health makes you a good candidate for their prescription ED medications. BlueChew should also be especially appealing to men who’ve had limited success with monotherapies in the past and would like to try a multitherapy like BlueChew Gold. BlueChew Gold sildenafil in 70mg, 90mg, and 110mg doses, with research generally using 25mg increments up to 100mg.32 That puts Gold consistently on the higher side of the range seen in both research and among competitors’ products. Tadalafil remains active in the bloodstream for a longer period; it can effectively combat ED for 24-36 hours.3 You can also take tadalafil daily and be ready for sex at any time. This added convenience is why both men and women have responded to study surveys that they generally prefer tadalafil over sildenafil citrate tables other PDE5 inhibitors, like sildenafil or vardenafil.35 However, Gold is only intended to be taken as needed, with the maximum monthly allotment from the company being just 24 doses.

Frequently asked questions

We regularly update the content here and across our site to keep availability information current. BlueChew’s lineup has evolved over the years, increasing in strength and variety as its customer base has grown and shown an interest in stronger medications and combinations. At first, BlueChew only offered sildenafil and tadalafil, the generic equivalents of Viagra and Cialis, respectively. The company then added vardenafil, a sildenafil alternative and the generic equivalent of Levitra. After that, the company launched its daily tadalafil and MAX and VMAX combination medications.

BlueChew vs. Viagra

Most recently, BlueChew’s catalog has coalesced around its most promising product, especially for men with treatment-resistant ED: BlueChew Gold. Gold combines four ED medications to tackle the problem from multiple angles. Sildenafil: A PDE5 inhibitor and the active ingredient in Viagra, sildenafil works in as little as 15 minutes and lasts up to eight hours.2 Tadalafil: Another PDE5 inhibitor and the active ingredient in Cialis. Tadalafil kicks in after as little as 15 minutes and lasts up to 36 hours.3 Apomorphine: A dopamine agonist that supports erectile performance by improving brain chemistry.36 Oxytocin: The so-called “love hormone,” oxytocin can improve mental health markers like depression and anxiety, which can worsen or even cause ED.24 For most men with ED, the combined ingredients in BlueChew Gold will be effective in treating erectile dysfunction.27 28 This means most men will be able to use it in order to achieve an erection of sufficient strength and duration for sex. BlueChew’s innovation on these traditional and effective medications is that it offers them combined as multitherapies able to dissolve under the tongue to start working even faster.29 Sildenafil (the active ingredient in Viagra) has been proven effective in numerous clinical studies, as has tadalafil (the active ingredient in Cialis).2 3 Sildenafil and tadalafil are classified as PDE5 inhibitors. Unlike PDE5 inhibitors, which work to control enzymatic activities that influence blood flow, apomorphine works in the brain as a dopamine receptor agonist, which essentially tricks the brain into behaving as though there’s more dopamine present than there is in fact.36 Dopamine — a critical neurotransmitter — plays important roles in male sexual health and behavior, with imbalances in neurochemistry that contribute to ED earning their own designation as neurogenic erectile dysfunction.37 23 Including apomorphine in an ED treatment regimen can help offset neurochemical imbalances that might be contributing to — or even be the root cause of — ED. Low doses are common in this space, with BlueChew offering 2mg, 3mg, and 4mg apomorphine doses in Gold, alongside sildenafil, tadalafil, and oxytocin. And while some comparative studies show that a common sildenafil dose (50mg) can outperform a common apomorphine dose (3mg), other comparisons show similar performance and highlight apomorphine’s quick onset of action, even at just a 2mg dose.38 39 Oxytocin is a hormone associated with social bonding to such an extent that some researchers have taken to calling it the “love hormone.”40 It’s been studied extensively in the context of women’s sexual health, but its potential to treat physiological causes of ED hasn’t been established.

Chemical synthesis

Let’s take a close look now at each ingredient in Gold, to better understand how they fight ED: Whether or not most men realize it, this is the most well-known medication for fighting ED; it’s the generic form of Viagra, the original little blue pill. Once it kicks in, which takes about 30-60 minutes, it lasts between four and six hours. BlueChew Gold sildenafil in 70mg, 90mg, and 110mg doses, with research generally using 25mg increments up to 100mg.32 That puts Gold consistently on the higher side of the range seen in both research and among competitors’ products. Tadalafil remains active in the bloodstream for a longer period; it can effectively combat ED for 24-36 hours.3 You can also take tadalafil daily and be ready for sex at any time. This added convenience is why both men and women have responded to study surveys that they generally prefer tadalafil over sildenafil citrate tables other PDE5 inhibitors, like sildenafil or vardenafil.35 However, Gold is only intended to be taken as needed, with the maximum monthly allotment from the company being just 24 doses.

How does BlueChew work?

Unlike PDE5 inhibitors, which work to control enzymatic activities that influence blood flow, apomorphine works in the brain as a dopamine receptor agonist, which essentially tricks the brain into behaving as though there’s more dopamine present than there is in fact.36 Dopamine — a critical neurotransmitter — plays important roles in male sexual health and behavior, with imbalances in neurochemistry that contribute to ED earning their own designation as neurogenic erectile dysfunction.37 23 Including apomorphine in an ED treatment regimen can help offset neurochemical imbalances that might be contributing to — or even be the root cause of — ED. Low doses are common in this space, with BlueChew offering 2mg, 3mg, and 4mg apomorphine doses in Gold, alongside sildenafil, tadalafil, and oxytocin. And while some comparative studies show that a common sildenafil dose (50mg) can outperform a common apomorphine dose (3mg), other comparisons show similar performance and highlight apomorphine’s quick onset of action, even at just a 2mg dose.38 39 Oxytocin is a hormone associated with social bonding to such an extent that some researchers have taken to calling it the “love hormone.”40 It’s been studied extensively in the context of women’s sexual health, but its potential to treat physiological causes of ED hasn’t been established. However, because around 40% of all ED cases are psychogenic, or psychological in origin, oxytocin’s potential to treat psychiatric issues makes it a prime candidate for ED treatment.26 24 This potential is further supported when you realize the complex interconnection between ED and mental health concerns like depression and anxiety.41 One can lead to the other, and either can make the other worse. Treating ED from both physiological and psychological perspectives may be the most efficacious pathway for most men. However, because around 40% of all ED cases are psychogenic, or psychological in origin, oxytocin’s potential to treat psychiatric issues makes it a prime candidate for ED treatment.26 24 This potential is further supported when you realize the complex interconnection between ED and mental health concerns like depression and anxiety.41 One can lead to the other, and either can make the other worse. Treating ED from both physiological and psychological perspectives may be the most efficacious pathway for most men. BlueChew’s tablets consist of more than just the active drugs they provide. To get those drugs into a convenient chewable or dissolvable form, the company compounds them with several inactive ingredients that allow the tablets to hold their shape, taste relatively good, and break down easily in the mouth. As we mentioned at the top, ED isn’t some rare and shameful disorder; it affects about a third of all men. Of course, the prevalence of ED increases with age, but that doesn’t mean it’s unheard of among young men, either. About 5% of men under age 40 are unable to achieve an erection,6 and numerous medications can include ED as a potential side effect, including two popular hair loss treatments, finasteride and dutasteride.44 Other factors can contribute to ED, as well, including both physiological and psychological issues.

Proper Use

BlueChew’s tablets consist of more than just the active drugs they provide. To get those drugs into a convenient chewable or dissolvable form, the company compounds them with several inactive ingredients that allow the tablets to hold their shape, taste relatively good, and break down easily in the mouth. As we mentioned at the top, ED isn’t some rare and shameful disorder; it affects about a third of all men. Of course, the prevalence of ED increases with age, but that doesn’t mean it’s unheard of among young men, either. About 5% of men under age 40 are unable to achieve an erection,6 and numerous medications can include ED as a potential side effect, including two popular hair loss treatments, finasteride and dutasteride.44 Other factors can contribute to ED, as well, including both physiological and psychological issues.

Marketing and sales

These can play off one another to exacerbate ED the longer you suffer from it. Ultimately, anything that can inhibit blood flow to the penis can be considered an organic cause, including: But it’s just as likely that there are other factors at play, including: In fact, mental health concerns resulting in or contributing to ED — also known as psychogenic ED — account for around 40% of all ED cases. (To learn more, you can also visit our complete guide to erectile dysfunction treatments.) At first glance, it’s clear that some men may overcome a few of these causes with lifestyle interventions such as quitting smoking, improving diet and exercise, or working to reduce stress. Those interventions are well worth pursuing but can take time, and there’s no harm in seeking prescription help from BlueChew in the meantime. Men who struggle with ED may be able to get an erection for a short canadian sildenafil citrate duration, or they may not be able to become erect at all. These can play off one another to exacerbate ED the longer you suffer from it.

Sildenafil 45 mg chewable tablets are used to treat erectile dysfunction.
They provide faster absorption compared to standard tablets.
The chewable form allows easier swallowing for some users.
Typically taken before sexual activity as directed by a doctor.
Do not consume more than one tablet in 24 hours.
Common side effects include headache, flushing, and dizziness.
These tablets should be used with caution by those with heart issues.
Avoid alcohol consumption when taking sildenafil chewables.
Store tablets in a cool, dry place away from children.
Consult a doctor if you experience prolonged erections.
Sildenafil 45 mg is a higher dose for more severe cases.
Discontinue use if allergic reactions like rash occur.

Ultimately, anything that can inhibit blood flow to the penis can be considered an organic cause, including: But it’s just as likely that there are other factors at play, including: In fact, mental health concerns resulting in or contributing to ED — also known as psychogenic ED — account for around 40% of all ED cases. (To learn more, you can also visit our complete guide to erectile dysfunction treatments.) At first glance, it’s clear that some men may overcome a few of these causes with lifestyle interventions such as quitting smoking, improving diet and exercise, or working to reduce stress.

Drug Class	Interaction Type	Effect on Sildenafil	Notes
Nitrates	Dangerous	Severe hypotension	Contraindicated due to risk of life-threatening hypotension
Alpha-blockers	Caution	Enhanced effect	May cause hypotension; monitor blood pressure
CYP3A4 inhibitors	Increased levels	Elevated testosterone	Risk of side effects; dose adjustment may be needed
Protease inhibitors	Significant increase	Elevated plasma levels	Use caution; consider dose reduction

Those interventions are well worth pursuing but can take time, and there’s no harm in seeking prescription help from BlueChew in the meantime.

Generic sildenafil offers a cost-effective alternative.
Safe use requires understanding potential drug interactions.
Chewable tablets are more convenient for some users.
Avoid grapefruit or grapefruit juice while using sildenafil.
Sexual activity carries risks for individuals with heart conditions.
Sildenafil can cause vision disturbances like blue tint.
Take care to adhere to prescribed dosing schedules.
Be aware of the possibility of priapism, a prolonged erection.
Use with caution if you are prone to low blood pressure.
Always read the patient information leaflet carefully.
Notify your doctor if pregnant or breastfeeding.
Remember to stay hydrated while on medication.

Men who struggle with ED may be able to get an erection for a short canadian sildenafil citrate duration, or they may not be able to become erect at all. For the many men affected by ED, the condition can be an unfortunate source of embarrassment and frustration. It’s important to remember that this is a very common health condition, and treatment options are available. BlueChew is worth exploring if you’ve noticed difficulty getting or keeping an erection in order to enjoy sex.

How do I get started with BlueChew?

Through the medical consultation, BlueChew will be able to determine if your underlying health makes you a good candidate for their prescription ED medications.

Sildenafil 45 mg chewables are effective for erectile dysfunction.
Always review the contraindications with your healthcare provider.
They are designed for fast onset within 30 minutes.
Alcohol consumption can impair the drug’s effectiveness.
Taking the medication with a high-fat meal may delay effects.
Not suitable for use with certain blood pressure medications.
Use as part of a comprehensive treatment plan.
If your erection lasts longer than 4 hours, seek medical help.
Keep track of any unusual symptoms or reactions.
Do not attempt to increase the dose without medical advice.
Use the medication strictly according to your doctor’s instructions.
Sexual activity should be preceded by stimulation for results.

BlueChew should also be especially appealing to men who’ve had limited success with monotherapies in the past and would like to try a multitherapy like BlueChew Gold.

Usual Geriatric Dose for Erectile Dysfunction

This chewable and dissolvable tablet provides two PDE5 inhibitors in one treatment, alongside two additional medications intended to treat ED from different angles than traditional therapies. This chewable and dissolvable tablet provides two PDE5 inhibitors in one treatment, alongside two additional medications intended to treat ED from different angles than traditional therapies.