Dapoxetine for premature ejaculation

Priligy > priligy tablets


The most common side-effects include feeling dizzy or faint, and feeling sick (nausea).

  • Priligy can be effective in improving sexual confidence.
  • Combining therapy with counseling may yield better results.
  • Do not take Priligy if you are allergic to dapoxetine.
  • The medication is not a cure but manages symptoms of PE.
  • It is only suitable for men with diagnosed premature ejaculation.
  • Avoid heavy machinery or driving after taking Priligy.
  • The medication should not be crushed or broken.
  • Use with caution in combination with other prescribed drugs.
  • Discuss possible interactions with your healthcare provider.

Drinking a full glass of water at the same time as taking the tablet can reduce these effects. Premature ejaculation is the term used when a man orgasms (ejaculates) more quickly than he and/or his partner would like.

Product Summary

Doctors define premature ejaculation as ejaculation in less than 2 minutes from penetration. However, if you ejaculate with very little stimulation, or before you want, and it is leading to relationship difficulties, you may benefit from treatment. There is medication available - dapoxetine (Priligy) - but there are also physical treatments such as extra thick condoms or anaesthetic (numbing) creams and sprays, and condoms pre-coated with numbing gel, which reduce penile sensitivity. These can be bought in many pharmacies without the need for a prescription. As premature ejaculation is often linked to stress and psychological factors, psychological therapies can help.

Precautions when taking Priligy 60mg

See NHS - Ejaculation problems or the book Coping with Premature Ejaculation: How to Overcome PE, Please Your Partner, and Have Great Sex (2004) by Michael E. Metz. There are a few medical conditions where it would be unsafe to take Priligy. Checks are carried out within the Priligy online consultation. The license for dapoxetine states that Viagra (sildenafil), Cialis (tadalafil), and other erectile dysfunction drugs should not be used together with Priligy as there is a risk of very low blood pressure. For some men it can be temporary and can get better on its own; for others, prescribed treatments such as dapoxetine tablets can be helpful. Dapoxetine is a selective serotonin reuptake inhibitor medicine which has been specially developed for the treatment of premature ejaculation. It increases the time it takes to ejaculate and can improve the control over the ejaculation. It starts to work very quickly, so it is taken when you anticipate having sex, rather than every day.

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You have to take it 1-3 hours before you have sex. Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking dapoxetine it is important that your doctor knows: If you have a tendency to faint.

Quick tips

If you suffer from both erectile dysfunction (ED) and premature ejaculation (PE) try treatment for ED first and if you still have PE problems discuss this with your regular doctor who may be able to prescribe these together following a more in depth review. Priligy (dapoxetine) was developed after it was realised that a side effect of taking SSRI antidepressants was to prolong erections. It was specifically designed as a short acting medication rather than an antidepressant but acts in the same way to increase serotonin levels in the brain, which delays ejaculation. It is washed out of the system within around 20 hours (half-life approximately 1.5 hours) and has no antidepressant effect. There are two strengths of dapoxetine (Priligy) tablets: 30mg and 60mg.

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You should start with the lower 30mg strength, taking the tablet 1-3 hours before sexual intercourse. Swallow the tablet whole, with a full glass of water. The strength of tablet can be increased the next time, if the lower dose does not have the desired response and you had no significant side effects. You should not take a dose more than once every 24 hours and do not take it every day. It is possible that grapefruit juice will cause the dapoxetine (Priligy) to stay in your system longer, so you should wait 24 hours after drinking grapefruit juice before taking dapoxetine. If you have a tendency to faint.

The Role of Dapoxetine in Modern Urological and Sexological Practice

Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet. How do I know if I have premature ejaculation? What treatment is available for premature ejaculation? Can I take erectile dysfunction drugs with dapoxetine (Priligy)? What are the side effects of dapoxetine (Priligy)?

Access medical and health information

How can I reduce the risk of side effects of dapoxetine (Priligy)? Premature ejaculation (PE) is actually quite common. Up to 30% of men suffer with PE problems at some time in their life. It is usually related to stress and psychological factors rather than a physical problem. There are a variety of ways to help. If you have a bleeding or clotting disorder. If you have ever had a mental health problem causing 'high' or 'low' moods, such as bipolar disorder, depression or mania.

  • Priligy has been shown to improve interpersonal confidence.
  • The medication should be part of a broader treatment plan.
  • Rarely, Priligy can cause mood swings or confusion.
  • Take Priligy at the same time before planned sexual activity.
  • Discontinue use if you experience severe allergic reactions.
  • Dapoxetine has a rapid clearance from the body.
  • It is important to adhere strictly to dosing guidelines.
  • Do not share your medication with others.
  • Contact your healthcare provider if you notice unusual symptoms.

If you have increased pressure in your eye, a condition called glaucoma. If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.

  • Schedule a medical assessment before starting Priligy.
  • Follow dosing instructions precisely to avoid adverse effects.
  • Report any severe side effects to your doctor immediately.
  • Do not mix Priligy with other serotonergic drugs.
  • Use only the prescribed dose for your condition.
  • Avoid using Priligy with other medications for depression.
  • The medication does not provide protection against STDs.
  • Priligy has a quick onset, usually within 1 hour.
  • Regular check-ups are recommended for long-term use.

If you have ever had an allergic reaction to a medicine. If you are taking any other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about dapoxetine, and will also provide you with a full list of the side-effects which you could experience from taking it. Take dapoxetine exactly as your doctor tells you to. Drink a full glass of water at the same time as you take a tablet.

Country Average Price (per tablet) Insurance Coverage Availability
USA $10 - $15 Varies Widely available
UK £8 - £12 Some plans Prescription required
Canada CAD 12 - CAD 18 Usually covered Available at pharmacies

The recommended starting dose is one 30 mg tablet, taken 1 to 3 hours before you anticipate having sex. Your doctor may later decide to increase your dose to one 60 mg tablet. Your doctor will only prescribe the higher dose for you if the 30 mg dose is insufficient, and providing you have not experienced any side-effects such as feeling faint.

How common is premature ejaculation?

Priligy should not be taken by women. Do not drink grapefruit juice at least 24 hours prior to taking Priligy as this can increase the levels of the medication in your body. Avoid drinking alcohol while taking Priligy as consuming alcohol while taking Priligy can intensify dizziness, sleepiness, and slow reactions. Priligy can cause sleepiness, dizziness, fainting, trouble concentration, and blurred vision. Avoid driving or operating heavy machinery until you know how the medication affects you.

Can I buy Priligy over the counter?

Talk to your doctor before taking Priligy if you are lactose intolerant. If you develop side effects that are persistent or troublesome, immediately talk to your doctor. The most common side effects associated with taking Priligy include the following: dizziness, headache, feeling sick, mood changes, numb or tingling sensation, difficulty getting or keeping an erection, excessive sweating or flushing, diarrhea, constipation, stomach pain, bloating, sleep problems, strange dreams, tiredness, sleepiness, nasal congestion, high blood pressure, difficulty concentration, shaking or trembling, low desire to have sex, ringing in the ears, blurred vision, indigestion, and dry mouth. IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Do not take more than one tablet in any 24 hours. Dapoxetine is not intended for regular daily use - you should only take it before you anticipate having sex. The tablet has a bitter taste, so swallow it whole without chewing.

Side Effect Frequency Severity Notes
Nausea Common Mild Usually transient
Headache Common Mild Can be treated with analgesics
Dizziness Less common Mild Post-dose, avoid driving
Insomnia Less common Mild Sometimes reported

You can take it either with or without food.

How to take dapoxetine tablets

Grapefruit juice is a weak inhibitor of CYP3A4 gut wall metabolism, which can lead to a rise in levels of many drugs in your blood. Men usually get on well with dapoxetine (Priligy). The most common side effects are dizziness due to lower blood pressure, nausea, and headache. The full list of side effects is in the patient information leaflet. You are more likely to have side effects if taking alcohol, recreational drugs (such as LSD, heroin, methadone), or sleeping tablets at the same time as Priligy.

Q. How should I take Priligy 60mg?

There are some interactions with other drugs and some herbal remedies. The online consultation questionnaire checks if your medication is unsuitable to take with Priligy. Priligy is only licensed for use by men aged for sale priligy between 18 and 64 years. The effectiveness and safety of Priligy has not been established in patients aged 65 years and over. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption should not take dapoxetine (Priligy). Make sure you keep your follow-on appointments with your doctor. This is so your doctor can check on your progress.

  • Priligy is a medication used to treat premature ejaculation in men.
  • Its active ingredient is dapoxetine, a fast-acting SSRI.
  • Priligy is usually taken 1-3 hours before sexual activity.
  • The recommended dose varies between 30 mg and 60 mg.
  • Do not exceed more than one tablet per 24 hours.
  • Common side effects include dizziness, headache, and nausea.
  • Consult a doctor before use, especially if on other medications.
  • Priligy is approved in many countries for erectile health.
  • It is not intended for daily use but as needed before intimacy.

Do not drink alcohol whilst taking dapoxetine, as it might increase the sedative effects of the alcohol. It can also increase the risk of fainting.

Country Approval Status Regulatory Body Notes
United States Approved by FDA FDA Prescription required
European Union Approved by EMA EMA Prescription required
Australia Approved by TGA TGA Prescription required

Do not use any recreational drugs while you are taking dapoxetine, as this could lead to you experiencing serious side-effects.

See also

Most men benefit from dapoxetine (Priligy), but psychological therapies and direct physical treatments can be used at the same time and may increase the benefit. Priligy was first launched in the UK in 2013 and remained under patent until October 2025, so only the drug company Menarini could produce and sell the medicine. When the patent expired, lower cost generic/unbranded versions became available and Menarini decided to no longer market Priligy. Dapoxetine is available on prescription in some NHS health authority areas, usually after specialist referral and advice - please check with your local GP surgery. NHS doctors will also usually be able to write private prescriptions for dapoxetine (charges will apply).

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Authored 28 July 2020 by Dr A. Reviewed by Dr C. Pugh, Dr B. Babor Last reviewed 19 June 2023 Last updated 3 December 2025 Editorial policy Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 14 Apr 2025 Dapoxetine is prescribed for the treatment of premature ejaculation. Take one tablet 1-3 hours before you have sex. A chemical in grapefruit juice can increase the amount of dapoxetine in your bloodstream and this increases the risk of side-effects. If you do drink grapefruit juice, do not take a dapoxetine tablet for at least 24 hours afterwards.